Karnataka PGET Dermatology MCQ Answer 5
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Scl-70 antigen is the nuclear enzyme topoisomerase 1. Approximately 20-30% of patients with scleroderma have antibodies to Scl-70. The antibody is rarely seen in other conditions. Scl-70 antibody are usually present in the diffuse subtype of scleroderma while antibodies to centromere proteins are dominant in the limited subtype of scleroderma or CREST syndrome.
Tags: MCQ, Dermatology, Scl-70, antibody
Category: Karnataka PGET 2007 MCQs
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