Typical features of a squamous cell carcinoma of the lung include all except:

1. 
   
   
   Hypercalcemia
2. 
   
   
   Central location
3. 
   
   
   Fungating mass
4. 
   
   
   Mucin production
5. 
   
   
   Keratin pearls

Answer

At which age does the American Cancer Society suggest routine yearly mammograms if there are no known risk factors in an asymptomatic woman?


A. 20 years of age
B. 35 years of age
C. 40 years of age
D. 45 years of age

Answer

Which of the following is NOT a risk factor associated with the development of breast carcinoma?


A. Cigarette smoking
B. Heavy alcohol consumption
C. Gene mutation in BRCA 1
D. Postmenopausal obesity

Answer

Which of the following tumors arise from the intralobular stroma?

A. Liposacrcoma
B. Fibroadenoma
C. Large duct papilloma
D. Invasive ductal carcinoma

Answer

Klatskin's tumor is:


A. An endocrine pancreatic tumor secreting vasointestinal polypeptide
B. Adenocarcinoma at the confluence of the right and left extrahepatic bile ducts
C. Adenocarcinoma in the head of the pancreas
D. Sarcoma in the tail of the pancreas

Answer

Human papilloma virus has been identified in all of the following lesions EXCEPT:


A. Hairy leukoplakia

B. Nasopharygeal carcinoma

C. Papillomatosis

D. Laryngeal squamous cell carcinoma

Answer

The tumor with the best long term prognosis:

A. Squamous cell carcinoma
B. Adenocarcinoma
C. Small cell undifferentiated carcinoma
D. Bronchial carcinoid
E. Large cell undifferentiated carcinoma

Answer

A 55 year old long term smoker, a long term IRS agent, presents for his routine physical examination and is found to have a 4 cm left peripheral lung nodule and enlarged hilar lymph nodes. He is afebrile and feels well except for some mild shortness of breath on exertion. Further CT scans show that he is normocalcemic. A peripheral CT directed lung biopy shows cells with nuclear pleomorphism, prominent nuclei and abundant pink to foamy cytoplasm. Abnormal mitosis are everywhere, and part of the tissue is necrotic. A special stain develops intra-cytoplasmic mucin substances.


Your diagnosis:


A. Squamous cell carcinoma
B. Adenocarcinoma
C. Small cell undifferentiated carcinoma
D. Bronchial carcinoid
E. Hamartoma

Answer

The tumor most responsive to chemotherapy:


A. Squamous cell carcinoma
B. Adenocarcinoma
C. Small cell undifferentiated carcinoma
D. Bronchial adenoma
E. Large cell undifferentiated carcinoma

Answer

Malignant mesothelioma:

A. Associated with previous asbestos exposure

B. Increased risk with cigarette smoking

C. Presents with central lung nodule

D. Responds to chemotherapy, with a 50% 5 year survival

Answer

Twenty to thirty 1-2 cm nodular densities are found in both lower lung fields on a chest radiograph in a 55 year old man. He has a recent history of rectal bleeding and a 20 pound weight loss over the last months. He is a life long non-smoker. He is afebrile and denies pulmonary symptoms such as shortness of breath or a productive cough. Your most likely preliminary diagnosis:


A. Bronchopneumonia
B. Metastatic colon carcinoma
C. Primary tuberculosis
D. Pulmonary hamartoma
E. Bronchial carcinoid

Answer

A 74 year old man has a slowly growing parotid mass growing on his right arm. It is 3cm in diameter on evaluation, and 1 cm lesion is also found in his right paroid gland. the right lesion is excised and is well circumscribed. It is charecterized by small cystic spaces lined by cells with very granular pink cytoplasm. Abundant lymphocytes are seen in the supporting stroma. Your diagnosis:

A. Pleomorphic adenoma
B. Warthin tumor (adenolymphoma)
C. Adenoid cystic carcinoma
D. Mucoepidermoid carcinoma

Answer

Alpha-fetoprotein elevated in serum, also found in tumor cells by immunohistochemistry.

A. Hepatocellular carcinoma
B. Cholangiocarcinoma
C. Both A and B
D. Neither A or B

Answer

Fibrolamellar variant of this tumor is associated with a better survival rate is

A. Hepatocellular carcinoma
B. Cholangiocarcinoma
C. Both A and B
D. Neither A or B

Answer