An important step in protein synthesis is transcription. Which of the following statement(s) is/are true concerning this process?
- The first step in gene transcription involves separating the double helix of DNA by an enzyme known as DNA polymerase
- The initial product of DNA transcription is called heterogeneous nuclear RNA which codes directly for proteins
- After processing is complete, the mRNA is exported from the nucleus to the cytoplasm
- Only one protein can be produced from an initial mRNA strand
Answer
A patient with familial hypercholesterolemia undergoes a detailed serum lipid and lipoprotein analysis. Studies demonstrate elevated cholesterol in the form of increased LDL without elevation of other lipids. This patient's hyperlipidemia is best classified as which of the following types?
A. Type 1
B. Type 2a
C. Type 2b
D. Type 3
E. Type 5
Answer
A 5 year old child has massive liver enlargement and severe persistent hypoglycemia and ketosis. which of the following disease classes should be suspected?
A. Diabetes
B. Glycogen storage disease
C. Lysosomal storage disorder
D. Mucopolysaccharidoses
E. Urea Cycle defect
Answer
The lipoprotein sub-fraction associated with the term "good" cholesterol is:
A. Very low density lipoprotein (VLDL)
B. Low density lipoprotein (LDL)
C. High density lipoprotein (HDL)
D. Pre beta lipoprotein (PBL)
Answer
Tags:
MCQ, Biochemistry, Good Cholesterol
The blood level of total cholesterol concentration recommended by the National Institute of Health is:
A. Less than 250 mg/dl
B. Less than 225 mg/dl
C. Less than 200 mg/dl
D. Less than 150 mg/dl
Which of the following constituents is not usually found in Bile
?
-
cholates
-
phospholipids
-
deoxycholates
-
phosphodeoxycholates
-
ursodeoxycholates
Answer
Tags:
MCQ, Biochemistry, Bile
Which protein can bind four oxygen molecules?
a) Protein C
b) Raf proteins
c) G-protein
d) de-oxy hemoglobin
e) Glycogen Phosphorylase
Answer
Which protein contains two beta chains?
a) Protein C
b) Raf proteins
c) G-protein
d) de-oxy hemoglobin
e) Glycogen Phosphorylase
Answer
Which substance is constituted from eight water-soluble vitamins ?
a) vitamin B complex
b) complex carbohydrates
c) coenzyme Q10
d) amino acids
e) folic acid
Answer
A 35 year old man has been kept on long term parenteral nutrition in an intensive care unit after incurring severe head and abdominal injuries in a traffic accident. He has been receiving broad-spectrum antibiotics for prolonged periods due to recurrent chest and abdominal infections. He develops a hemorrhagic diathesis. His Prothrombin time is found to be increased. These manifestations are most likely secondary to a deficiency of
a) Vitamin A
b) Vitamin D2
c) Calciferol
d) Vitamin K
e) Vitamin C
Answer
The oxygen–haemoglobin dissociation curve is shifted to the left by a rise in?
a) carboxyhaemoglobin
b) 2,3-DPG (2,3-diphosphoglycerate)
c) plasma temperature
d) blood CO2 content
e) plasma H+ concentration
Answer
A 65-year old male hospital in-patient has smoked cigarettes since he was 18 years old. He has a chronic cough and marked sputum production. When his doctor starts to give him the usual talk about losing weight, he explains that since he has about fifty pounds to lose, he has tried to exercise, but is unable to because of shortness of breath with any activity. Upon further questioning, he comments that his symptoms have been present for a very long time, but he was hospitalized due to a marked exacerbation of his complaints. On auscultation, rhonchi and wheezes are heard.His laboratory results are as follows:
- pCO2 60 mm Hg(35-45 mm Hg)
- pH 7.34( 7.35-7.45)
- bicarbonate 31 mEq/L( 24 mEq/L)
- Na+ 140 mEq/L( 135-145 mEq/L)
- K+ 4.0 mEq/L( 3.5-5.5 mEq/L)
- Cl-100 mEq/L(98-109 mEq/L)
What is the primary disorder?
a) metabolic acidosis with a normal anion gap
b) metabolic acidosis with an elevated anion gap
c) metabolic alkalosis
d) respiratory acidosis
e) respiratory alkalosis
Answer
