MCQ Hematology Answer 34
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Pernicious Anemia
Common disorder: prevalence circa 0.1%: peak 60 yrs: M:F 1:2.
There is an autoimmune attack on the gastric parietal cell manifest histologically as atrophic gastritis. Patients are unable to secrete acid or intrinsic factor. There is a significant association with vitiligo and thyroid disease. There may be a family history of Pernicious Anemia and thyroid disease. Intrinsic Factor autoantibodies are present in the serum of 50-75% of cases, and are highly specific.
Tags: MCQ, Hematology, Pernicious Anemia
Category: Hematology MCQs
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