MCQ Psychiatry Answer 11

The Correct Answer is D


Antidepressants that inhibit serotonergic reuptake have been reported to interfere with sexual function. Bupropion is a norepinephrine and dopamine reuptake inhibitor with essentially no direct serotonergic activity. Improvement in sexual functioning has been reported when sustained-release bupropion was either substituted for other antidepressants or added to a regimen of SSRIs.


Two recent studies have also shown that sustained-release bupropion was well tolerated in the treatment of hypoactive sexual desire disorder (HSDD) in non-depressed women.


Ref:
1) Modell JG, May RS, Katholi CR: Effect of bupropion-SR on orgasmic dysfunction in nondepressed subjects: A pilot study. J Sex Marital Ther 2000;26(3):231-240.
2) Segraves RT, Croft H, Kavoussi R, et al: Bupropion sustained release (SR) for the treatment of hypoactive sexual desire disorder (HSDD) in nondepressed women. J Sex Marital Ther 2001;27(3):303-316. (ABFM, 2002).

Category: Psychiatry MCQs