MCQ Hematology 10
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A 14-year old girl is referred for evaluation generalized adenopathy, hepatosplenomegaly and a Coombs positive hemolytic anemia. The patient has a younger sister with mild adenopathy and splenomegaly. Pertinent laboratory findings include an Hb of 9.0 gm/dl, 340,000 reticulocytes/l, polyclonal hypergammaglobulinemia, and the presence of a circulating double negative T lymphocyte population ( CD3+, CD4-, CD8- ). What test would be most likely to confirm your diagnosis ?
- HIV serology
- Marrow cytogenetic study.
- Fas mutation analysis.
- T cell receptor gene rearrangement study.
- Immunoglobulin gene rearrangement study.
Tags: MCQS, Hematology, Autoimmune
Category: Hematology MCQs
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