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COMEDK 2007 MCQ Answer 180
The correct answer is
DSummary of Leprosy - Infection with Mycobacterium leprae
- Bacteria multiply in the macrophages and Schwann cells of peripheral nerves
- Clinical spectrum: from tuberculoid (paucibacillary) to lepromatous (multibacillary)
- Thickened nerves with neuritis: trophic, motor and sensory disturbances
- Neuropathy leads to paralysis, trophic ulcers, blindness, mutilations
- Skin : numb white area with elevated edge (TT) to diffuse infiltration with nodules (LL).
- In lepromatous leprosy also involvement of deeper tissues (testes, tongue, eyes, etc.)
- Diagnosis clinical, Ziehl staining of smears (skin lesion, nose, earlobe)
- Treatment of leprosy with dapsone, rifampicin, clofazimine
- Leprosy reactions: type 1 (change in immunologic defence) and type 2 (immune complex)
- The majority of infections do not give rise to symptoms (only to a positive lepromine test). After infection there is an incubation period of 2-15 years (the mycobacteria multiply slowly).
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1 comments:
thank you so much dr. bhat
only thing is that it took a lot of time,may be it was worth it.
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