COMEDK 2007 MCQ Answer 180

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The correct answer is D


Summary of Leprosy
  • Infection with Mycobacterium leprae
  • Bacteria multiply in the macrophages and Schwann cells of peripheral nerves
  • Clinical spectrum: from tuberculoid (paucibacillary) to lepromatous (multibacillary)
  • Thickened nerves with neuritis: trophic, motor and sensory disturbances
  • Neuropathy leads to paralysis, trophic ulcers, blindness, mutilations
  • Skin : numb white area with elevated edge (TT) to diffuse infiltration with nodules (LL).
  • In lepromatous leprosy also involvement of deeper tissues (testes, tongue, eyes, etc.)
  • Diagnosis clinical, Ziehl staining of smears (skin lesion, nose, earlobe)
  • Treatment of leprosy with dapsone, rifampicin, clofazimine
  • Leprosy reactions: type 1 (change in immunologic defence) and type 2 (immune complex)
  • The majority of infections do not give rise to symptoms (only to a positive lepromine test). After infection there is an incubation period of 2-15 years (the mycobacteria multiply slowly).

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1 comments:

Anonymous said...
1/17/2008 12:24 PM

thank you so much dr. bhat
only thing is that it took a lot of time,may be it was worth it.

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