Ulcerative Colitis Pathology
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Answer A. Only 20% have pancolitis or extensive colitis (beyond 60cm). 25% have disease limited to rectum. The absence of rectal involvement is rare and suggests a diagnosis of Crohns colitis. UC is more common in non smokers and exsmokers and in a subset of patients disease onset or flares can repeatedly triggered by cessation of smoking and remission can be induced by resumption of smoking or nicotine therapy. NSAIDs can lead to flare.
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