Scleroderma and Blind Loop syndrome

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USMLE Road Map: Immunology (LANGE USMLE Road Maps)Answer C.


In scleroderma severe enough to cause the blind loop syndrome, the intestinal musculature has been replaced by fibrous tissue and can not respond to pro-kinetic agents. The stasis may produce bacterial overgrowth and therefore, antibiotics may be helpful. In severe, intractable cases, TPN may be required.

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