Gastrinomas
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Although early studies suggested that gastrinomas occur primarily in the pancreas (A), earlier diagnosis and intervention indicates that the duodenum is a common site for tumor occurrence. This has significantly changed the surgical approach in these patients. Gastrinomas, as opposed to carcinoid tumors rarely occur in the stomach (B). Although metastatic disease to the bone has been reporte
d in patients with ZE syndrome, local lymph node and liver are the most common sites for metastatic disease (D).
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