Collagenous colitis
on
with
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Answer: D.
A sub epithelial collagen band of at least 10 microns is needed to make the diagnosis of collagenous colitis. Smaller bands may be seen in the setting of inflammation but
do not meet the criterion for collagenous colitis. Rectal biopsies may be negative in the setting of positive proximal biopsies due to the sometimes patchy distribution of the collagen band.
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