MCQ Pharmacology Answer 53
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Combining serotonergic medications such as SSRIs and MAO inhibitors can lead to the serotonin syndrome, a potentially fatal metabolic reaction. When switching from an SSRI to an MAO inhibitor, a washout period of five half-lives of the SSRI is recommended.
Ref: Sampson SM: Treating depression with selective serotonin reuptake inhibitors: A practical approach. Mayo Clin Proc 2001; 76(7):739-744.
Tags: MCQ, Pharmacology, Drug Interactions
Category: Pharmacology MCQs
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