MCQ Pharmacology Answer 52
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Trimethoprim/sulfamethoxazole (Bactrim) is a pregnancy category C antibiotic which is contraindicated in the third trimester of pregnancy because its sulfonamide component displaces bilirubin from albumin binding sites and thus can increase the free bilirubin concentration in the newborn's blood. This theoretically could increase the risk of the infant developing kernicterus, particularly preterm infants. The remaining antibiotics listed are pregnancy category B agents, which can be used safely throughout pregnancy.
Ref: Delzell IE Jr, Lefevre ML: Urinary tract infections during pregnancy. Am Fam Physician 2000; 61(3):713-721.
Tags: MCQ, Pharmacology, Pregnancy, Drugs
Category: Pharmacology MCQs
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