MCQ Pharmacology Answer 48
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While thiazide diuretics do not cause hypercalcemia by themselves, they can exacerbate the hypercalcemia associated with primary hyperparathyroidism. Thiazides decrease the renal clearance of calcium by increasing distal tubular calcium reabsorption. Furosemide tends to lower serum calcium levels and is used in the treatment of hypercalcemia. None of the other medications would be expected to significantly affect the serum calcium level in this patient.
Ref: Wilson JD, Foster DW, Kronenberg HM, et al: Williams Textbook of Endocrinology, ed 10. WB Saunders Co, 2003, p 1335.
Tags: MCQ, Pharmacology, Hypercalcemia
Category: Pharmacology MCQs
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