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Post Streptococcal Glomerulonephritis
Age/Sex: Childhood, 2:1 male predominance
Renal Presentation: Hematuria, Proteinuria, Red cell casts, oliguria
Systemic findings: Clinical presentation can vary from microhaematuria to a full blown nephrotic syndrome characterised by red-brown or smokey coloured urine, proteinuria, oedema, hypertension and acute renal failure
Pathology: Immune complexes, swelling of glomerular tufts, hypercellularity of glomeruli, proliferation of mesangial/epithelial/endothelial cells
Pathogenesis: Immune complex deposition in the glomeruli causing a decrease in GFR
Natural Course: Most recover w. no or mild therapy
Treatment: Antibiotics, maintain Na and H2O balanceCategory: Pathology MCQs
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