Radioactive Iodine in thyroid disease

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The Arctic Aeromedical Laboratory's Thyroid Function Study: A Radiological Risk and Ethical AnalysisThe correct answer is D

Explanation:


Iodine 131 is a radioactive isotope of iodine (RAI) that is selectively concentrated in the thyroid tissue and metabolized by the same pathways as naturally occurring iodine. This, together with its long half-life (8 days), allows it to deliver high doses of radiation to the thyroid gland (β-radiation) sufficient to destroy thyroid follicular cells. Thus, 131I is used in the treatment of Graves' disease, toxic multinodular goiter, and differentiated thyroid cancer. The doses of RAI used in the treatment of Graves' disease and toxic multinodular goiter are relatively low compared with those used in the treatment of thyroid cancer (in which it is used in conjunction with surgery). RAI has no place in the treatment of thyroid lymphoma because lymphoma cells do not concentrate iodine.


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