Terfenadine is an OTC antihistamine and there have been reports of serious cardiac arrhythmia's if given with erythromycin or systemic anti fungal agents. Ciprofloxacin causes a potentiation of theophyline levels, this drug has a narrow therapeutic window and therefore toxic effects can occur. Cimetidine potentiates the effect of oral anticoagulants including warfarin.
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