The correct answer is CLow maternal serum levels of α-fetoprotein may indicate fetal Down syndrome. Elevated maternal serum levels suggest the presence of a fetal neural tube defect and certain other congenital abnormalities. Other causes of increased maternal serum α-fetoprotein levels include twins, gestational age greater than originally estimated, fetal edema, and fetal demise.
Ref: Gabbe SG: Obstetrics: Normal and Problem Pregnancies, ed. 3. Churchill Livingstone Inc, 1996, pp 224-225. (ABFP, 2001,)
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Obstetrics MCQs
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