MCQ Pathology Answer 4
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The Correct Answer is D.
The movement of neutrophils from the vessel lumen into into a damaged area is mediated by substances known as chemotactic factors, which diffuse from the area of tissue damage. Time-lapse cine photography in experiments shows apparently purposeful migration of neutrophils along a concentration gradient. The main neutrophil chemotactic factors are:
- C5a
- LTB4
- Bacterial components
These factors bind to receptors on the surface of neutrophils and activate secondary messenger systems, stimulating increased cytosolic calcium, with resulting assembly of cytoskeletal specializations involved in motility.
Tags: MCQ, Pathology, Inflammation
Category: Pathology MCQs
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