COMEDK 2007 MCQ Answer 48
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The correct answer is C
Multiple Myeloma
Key clinical features
Well-defined osteolytic areas are visible in the bone of the calvaria (classical 'raindrop' lesions) (arrows).
Multiple Myeloma
Key clinical features
- 75% of patients are between 50-70 yoa and 2:1 male preponderance
- LB Pain is the cardinal initial symptom relieved with bedrest and aggravated with weight. With sciatica
- Bacterial infections occur in 10% of cases most respiratory in nature.
- Pathological fracture is common complication
- Bone Scans are cold
- Gross osteoporosis may be the only early sign
- Punched lesions are the radiologic hallmark of myeloma
- Vertebra plana or wrinkled vertebra is characteristic.
- Raindrop skull (lytic myeloma defects) and pedicle sign of myeloma (preservation of pedicles) occur.
- “Moth Eaten,” Permeative lesions
- Foggy cortical – Medullary border
- 40% show Bence Jones’ proteinuria.
- Immnoglobulin Electrophoresis – to Elevation of IgG
- May have infections due to decreased WBCs
- Normocytic, normochromic anemia
Well-defined osteolytic areas are visible in the bone of the calvaria (classical 'raindrop' lesions) (arrows).
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