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DConditions associated with non-immune hydrops fetalisHemolytic anemia -α-thalssemia-RBC enzyme deficiencies
Other anemias -Feto-maternal hemorrhage
-Twin-twin transfusion (donor)
Cardiac-Fetal arrhythmias
-Premature closure of foramen ovale
-Hypoplastic left heart
-Hypoplastic right heart
-Ebstein’s anomaly of tricuspid valve
-Cardiomyopathy
-Cardiac tumors
-Premature closure of ductus
arteriosus
-Other structural anomalies
Chromosomal abnormalities -Trisomy 21, 18
-Turner syndrome
Infections-
Viral (Parvovirus B19, Herpes,CMV)-Toxoplasmosis
-Syphilis
-Chagas Disease
Vascular malformations-Chorioangioma (placenta, umbilical
vessels)
-Liver hemangioma
-Cerebral A-V malformation
-Sacrococcygeal teratoma
-Klippel-Trenaunay syndrome
Vascular accidents -Intracranial hemorrhage
-Thrombosis of renal veins, IVC
-Twin-twin transfusion (recipient)
Lymphatic malformations-Pulmonary lymphangiectasis
-Cystic hygroma
-Multiple pterygium syndrome
-Noonan syndrome
Chest masses-Cystic adenomatoid malformation
-Diaphragmatic hernia
-Pulmonary sequestration
-Intrathoracic mass
Skeletal conditions-Asphyxiating thoracic dystrophy
-Osteogenesis imperfecta
-Chondrodysplasia
Genetic metabolic disease-Gaucher Disease
-Mucopolysaccharidosis
-Nieman-Pick Disease
-Neonatal hemochromatosis
Fetal Hypomobility-Arthrogryposis
-Neu-Laxova syndrome
-Pena-Shokier syndrome
-Myotonic dystrophy
CNS anomalies-Absent corpus callosum
-Encephalocele
-Holoprosencephaly
Other-Bowel obstruction with perforation
(meconium peritonitis, volvulus)
-Infant of diabetic mother
-Prune belly syndrome
-Congenital nephrosis
-Maternal indomethacin therapy
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