COMEDK 2007 MCQ Answer 127

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The correct answer is C

Psoriasis

Clinical:
  • Well demarc red plaques, silvery scale, commonly located on knees elbow, scalp
  • Auspitz sign: pinpoint bleeding, scale
  • May be assoc with severe arthritis

Pathogenesis:
  • Unknown but genetic factors play a role
  • entire epidermis can express disease
  • abnormal epidermal proliferation, transit time to surface reduced to 7 days from 28

Morphology:
  • Confluent plaques, parakeratosis, hyperplasia
  • PMNs in s.corneum, spongiform pustules, Munro microabcesses
  • thin suprapapillary plate, tortuous capillaries

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