Squamous cell carcinoma of Lung
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The Correct Option is D
- Squamous cell carcinoma occurs almost exclusively in smokers. It is a hilar/proximal cancer, usually starting in situ in the segmental bronchi. The tumors are often large, well- defined, and necrotic in the center. They have characteristics of squamous tissue, especially keratin pearls and desmosomes.
- Squamous cell carcinoma is easily diagnosed by sputum sample.
- Squamous cell carcinoma often has elevated PTH as part of a paraneoplastic disorder.
- Squamous lesions are atypical cells years before onset of lung cancer. They can only be detected by sputum samples. They represent squamous dysplasia and carcinoma in situ.
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