Sheehan's Syndrome

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The Pituitary Patient Resource Guide, Revised 4th EditionAnswer A

Sheehan's syndrome (mostly in patients who have experienced severe post-partum hemorrhage with hypotensive shock.

  • Post-partum ischemic necrosis of anterior pituitary
  • Failure of lactation, amenorrhea, atrophy of breasts, loss of pubic/axillary hair, superinvolution of uterus, hypothyroidism, adrenal cortical insufficiency
  • IV corticosteroids, fluids, and endocrinologic confirmation of diagnosis

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