Pharmacology MCQ 463

After administration of 100 micrograms of drug X the concentration of this drug in the circulating plasma was determined to be 0.2 nanogram/ml. Given these facts which of the following statements is TRUE?

A. The apparent volume of distribution is approximately 500 L indicating that the drug is chiefly bound to plasma proteins.

B. The apparent volume of distribution is approximately 0.002 L indicating that the drug is chiefly bound to plasma proteins.

C. The apparent volume of distribution is approximately 500 L indicating that the drug is hydrophobic and preferentially distributed to muscle and/or adipose tissue reservoirs.

D. The apparent volume of distribution is approximately 0.002 L indicating that the drug is hydrophobic and preferentially distributed to muscle and/or adipose tissue reservoirs.

E. The volume of distribution can not be determined without knowing the patient's weight.

Answer

Category: Pharmacology MCQs