Endocrinology MCQ 072

55 year old woman with history of goiterous hypothyroidism and a thyroid needle biopsy 10 years ago showing many Hurthle cells and lymphocytes. She complains now of an increase in the size of her left thyroid.

A. Optically clear nuclei lining glandular spaces and frond - like structures, with psammoma bodies

B. Sheets of pleomorphic cells with abundant cytoplasm, varying from spindle to round cells, with abundant abnormal mitoses

C. Sheets of small spindle cells between islands of amorphous pink material showing apple green birefringence on Congo red staining

D. Sheets of cells with abundant pink to orange cytoplasm, intercellular bridges and "pearl” formation.

E. Sheets of irregular small cells which are positive for LCA (leukocyte common antigen, a lymphocyte marker), on special stains.

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Category: Endocrinology MCQs