Karnataka PGET Medicine MCQ Answer 23
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Minimal Change Disease
- major cause of NEPHROTIC syndrome
- primarily a disease of small children (1-3 years of age)
- can be found in adult patients, but not as frequently
- glomeruli appear normal by LM
- By EM, there is effacement (fusion) of the epithelial foot processes
- “every patient that has proteinuria has effacement/fusion of the foot processes”
- IF is normal – no immune complex
- Basement membranes are normal
- good response to steroid therapy
- unknown etiology
- some circulating factor⇒ G-epithelial cell injury⇒ proteinuria
Tags: MCQ, Nephrology, Nephrotic syndrome
Category: Karnataka PGET 2007 MCQs
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