The correct answer is AIn type 1 diabetes the insulin-producing
β<-cells of the pancreas are destroyed. In the vast majority of these patients, the destruction is mediated by T cells . This is termed type 1A or immune mediated diabetes (IMD) . Islet cell autoantibodies comprise autoantibodies to islet cell-cytoplasm (ICA), to native insulin, referred to as insulin autoantibodies or IAA (208), to glutamic acid decarboxylase
(GAD65A) (209-211), and to two tyrosine phosphatases
{insulinoma associated antigens IA-2A (212) and IA-2
βA (213)
}.
Category:
Karnataka PGET 2007 MCQs
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