Craniopharyngioma

The correct answer is E
Explanation

Craniopharyngioma is the most common brain neoplasm of nonglial origin and the most common brain tumor associated with hypothalamic-pituitary dysfunction and sexual infantilism.

Clinical manifestations include headache, visual disturbances, short stature, symptoms of diabetes insipidus, and weakness of one or more limbs. Physical findings include visual defects (including bilateral temporal field deficits), optic atrophy or papilledema, and signs of GH deficiency, delayed puberty, and hypothyroidism. Although only a few patients seek evaluation because of short stature, most are below the mean in height and height velocity at the time of diagnosis.

Laboratory evaluation often indicates deficiencies in one or more pituitary hormones, including gonadotropins, GH, thyrotropin (thyroid-stimulating hormone [TSH]), corticotropin, and vasopressin (AVP). The plasma level of prolactin may be normal or increased. Radiographic examination often shows retarded bone age.

Tags: Endocrinology, MCQS, Craniopharyngioma

Category: