Immune system evasion and antigenic variation
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a) Capsules with sialic acid residues that prohibit alternative pathway activation
b) Group B and Group A streptococcal C5a-ase
2. Presence of antiphagocytic factors
a) Capsular polysaccharide
b) M-proteins
3. Genetic variation of surface proteins
a) Pili of GC
4. Inhibit phagolysosome fusion- mycobacteria
5. Scavenge reactive oxygen species- glycolipid of M. leprae
6. Block killing- hemolysins of L monocytogenes
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