AIIMS Nov 2006 - Pre Clinical MCQ Answer 41

Answer: 1. B Cells

Review:

Post-transplant lymphoproliferative disease (PTLD) is an unusual entity that has many of the features of immune system malignancy.


It is characterized by uncontrolled proliferation of B cells in a context of post transplant immunosuppression. In some situations, reducing the immunosuppression can reverse this proliferation. PTLD has emerged as a significant complication of solid organ transplantation. This entity was rarely reported until the mid 1980s, when the incidence began rising suddenly. PTLD presents significant problems for the clinician because it is difficult to predict and has high morbidity and mortality rates because of the difficulty in prevention and potential for graft loss.

Category: AIIMS Nov 2006 MCQs