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Predictors of Severity of Acute Pancreatitis
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C. Serum Amylase > 3x the upper limit of normal
Predictors of Severity of Acute Pancreatitis
- Clinical signs: peritonitis, shock, respiratory distress
- Ranson’s signs: 11 signs that include prognostic significance during the 1st 48 hours. A higher score means more severe disease.
- APACHE-II: sensitive and specific, can be calculated on admission
Ranson’s Criteria
On Admission
- Age > 55 years
- WBC > 16,000/mm3
- Blood Glucose > 200 mg/dl
- LDH > 350 IU/ L
- AST > 250 U/L
During the first 48 Hours
- Fall in Heamatocrit > 10%
- Serum Calcium <>
- Base deficit > 4m Eq/L
- Fluid Sequestration > 6 L
- BUN rises > 5mg/dl
- PaO2 <>
Risk of morbidity and mortality depends on patient’s score at 28 Hours
- Number of signs 0-2 3-4 5-6 7-8
- Percent mortality 0.9 16 40 100
- Percent morbidity 3.7 40 93 100
- > 7Days in the ICU
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