The Correct answer is B
Autoimmune pancreatitis is a type of chronic pancreatitis characterized by an autoimmune inflammatory process in which lymphocyte infiltration with associated fibrosis of the pancreas causes organ dysfunction.
Patients with autoimmune pancreatitis present with a wide variety of symptoms, but severe abdominal pain or acute pancreatitis is unusual.
Autoimmune pancreatitis
- an inflammatory process centered around the large pancreatic ducts
- presents as a pancreatic mass or diffuse swelling that mimics pancreatic cancer
- can also cause biliary strictures, mimicking PSC (primary sclerosing cholangitis)
- may affect other organs such as the lung or kidney
- imaging: on CT, pancreas is diffusely, abnormally enlarged
- microscopically, there are numerous plasma cells and lymphocytes around pancreatic ducts
- hallmark feature: IgG subtype 4 is elevated
- imaging: on ERCP, very narrowed pancreatic duct
- this is clinically important because treatment is simply medical (steroids) and the disease can be confused with cancer
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