MCQ Pathology Answer 21

The correct Answer is A

Asbestosis is a pneumoconiosis resulting from the inhalation of asbestos fibers. Asbestosis is a risk of shipyard workers, pipefitters, plumbers and insulation workers.

Exposure to asbestos induces a fibrotic reaction leading to progressive restrictive lung function and increased risk for cancer. Limitations on lung function demonstrated by a decrease in forced vital capacity (FVC) and a decrease in the diffusing capacity for carbon monoxide (DLCO) may actually precede the radiographic changes.

The pulmonary reaction consists of a widespread interstitial type fibrosis, which is frequently accompanied by diaphragmatic pleural calcifications. This interstitial reaction is indistinguishable from other types of interstitial fibrosis, except for the presence of the characteristic “asbestos (ferruginous) bodies”, which are actually asbestos fibrils coated with iron rich protein.

Interstitial fibrosis is the result of exposure to high concentrations of airborne asbestos fibers for approximately 10-20 years and although found in no more than 50% of heavily exposed workers, bronchiolar fibrosis may be the first and only early manifestation of asbestosis.

Category: Pathology MCQs