MCQ Pathology Answer 19

The correct answer is C

Idiopathic pulmonary fibrosis is a pulmonary disease characterized by interstitial fibrosis of unknown etiology. The pathology, which is non-specific, varies with the stage of the disease. The dominant pattern is inflammatory early on leading to organization of the exudate and interstitial fibrosis in the later stage. The severe septal thickening (fibrosis) leads to a "honeycomb" appearance of the lung and pronounced alveolocapillary block.

Although the course of idiopathic pulmonary fibrosis varies greatly from person to person, the disease usually develops slowly, sometimes over years.

Poorly understood pulmonary disorder characterized histologically by diffuse interstitial inflammation and fibrosis that in the advanced case results in severe hypoxemia and respiratory failure. It occurs in acute and chronic forms.

Chronic interstitial pneumonia has a clinical history lasting months or years with slowly increasing respiratory insufficiency, dyspnea, cough and finger clubbing. There is interstitial fibrosis, infiltration with lymphocytes and macrophages and microcyst formation. A common form is fibrosing alveolitis that is a progressive chronic pulmonary fibrosis of unknown etiology.

This occurs mostly in patients who range from 45 to 65 years of age. They present with increasing dyspnea and a dry cough. This progresses to respiratory failure with or without corpulmonale within about 5 years. Fatigue and considerable weight loss may occur.

Category: Pathology MCQs