MCQ Infection Answer 10
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Food poisoning is a toxemia associated with the ingestion of preformed microbial toxins. It is NOT an infection. Since the toxins are ingested preformed and no microbial growth within the human is required, symptomology occurs rapidly, usually within 2-12 hours.
Basteria responsible for a non-inflammatory, toxin mediated diarrhoea are:
- enterotoxin of C. perfringens
- neurotoxin of C. botulinum
- neurotoxin and enterotoxin of S. aureus and B. cereus.
Epithelial cell lysis is a microscopic pathologic effect of C. perfringens toxemia; rarely, with heavily contaminated foods, there is a diffuse, necrotizing enteritis of the jejunum, ileum and colon.
The pathology associated with C. botulinum is minimum, inconsistent and non-diagnostic.
- S. aureus - Vomiting (often projectile) little or no diarrhea, no fever. Symptoms occur within 1-4 hours after ingestion of contaminated food (generally mayonnaise or dairy products).
- B. cereus - Type 1: When the organism grows in starchy foods especially fried rice, there is emetic illness 2-3 hours after ingestion and a little diarrhea. No fever. Type 2: When the organism grows in meat or cream sauce or gravy there is profuse diarrhea with a little vomiting at 10-14 hours after ingestion. No fever.
- C. perfringens - Abrupt onset of profuse diarrhea with little or no vomiting about 12 hours after ingestion of meat. No fever.
- C. botulinum - Onset of symptoms between 6 hours and 8 days after ingestion of green beans, peppers, chili or sausage. The length of the incubation period is a function of the amount and antigenic type of toxin ingested. The illness is characterized by symmetric impairment of cranial nerves, followed in a descending pattern by weakness or paralysis of the muscles of the extremities and trunk.
Tags: Food poisoning, Bacteria, Botulinum, Bacillus cereus
Category: Infectious Diseases MCQs
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