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BToxic shock syndrome (TSS) is an illness marked by acute onset of fever, hypotension, rash, desquamation and failure of multiple organ systems. It is caused by a bacterial infection, predominantly Staphylococcus aureus, but also commonly caused by group A Streptococcus. Cases of TSS caused by other genera of bacteria (e.g. Clostridium sp.) have been reported as well.
Toxic shock syndrome is best known for its association with tampon use (menstrual toxic shock syndrome); however, there are many other causes of infection.
Transmission of staphylococcal TSS requires colonization with the bacteria, usually on a fomite placed inside the body or directly as in the case of burn patients whose wounds are susceptible to infection.
Toxic shock syndrome can be treated with antibiotics; antibiotic prophylaxis has been shown to be effective in high-risk burn patients
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