The correct answer is
BAST/ALT= Deritis ratio
- Usually is decreased with injury, since ALT rises more than AST.
- Injury include: viral hepatitis, toxic hepatic injury
- Exception: in alcoholic liver disease, the AST is > ALT so the Deritis ratio is increased.
A raised gamma glutamyltransferase is not confined to alcoholic liver disease as it can be induced by drugs (such as anticonvulsants, lipid lowering drugs, and oral contraceptives) and is also elevated in fatty liver disease. It is not always raised in chronic alcoholics, hence it is not sensitive for occult alcohol abuse.
The activity of alkaline phosphatase is increased up to 5-fold the upper limit of normal in situations where bile flow is obstructed. It is normal or only mildly elevated in hepatocellular damage.
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