COMEDK 2007 MCQ Answer 110
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The correct answer is B
Tamoxifen may cause changes in the lining of the uterus. An early sign of these changes may be abnormal vaginal bleeding or pelvic pain. After an average of 8 years of follow-up, the annual (per year) risk observed in a large-scale trial of breast cancer patients taking 20 mg of tamoxifen daily is about 2 per 1,000 women. This means that on the average, two cases of endometrial cancer were diagnosed among every 1000 women receiving tamoxifen during each year of the study and follow-up. This level of risk is approximately three times greater than that of a similar group of women in the general population.
Tamoxifen may cause changes in the lining of the uterus. An early sign of these changes may be abnormal vaginal bleeding or pelvic pain. After an average of 8 years of follow-up, the annual (per year) risk observed in a large-scale trial of breast cancer patients taking 20 mg of tamoxifen daily is about 2 per 1,000 women. This means that on the average, two cases of endometrial cancer were diagnosed among every 1000 women receiving tamoxifen during each year of the study and follow-up. This level of risk is approximately three times greater than that of a similar group of women in the general population.
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