118 MCQs in Pathology Answer

The Correct option is D


Leukoplakia is a clinical term that does not connote any specific histologic tissue alteration. Although leukoplakia has been overemphasized in its relationship to cancer, the etiology of any white lesion should be determined or monitored. The causes of leukoplakia are varied and include both intrinsic and extrinsic factors. Extrinsic factors include: tobacco, alcohol, and actinic radiation. Intrinsic factors include: vitamin deficiencies, immunodeficiencies, and genetic predisposition. A classic study by Waldron et al. revealed that 80% of these lesions showed benign changes such as hyperkeratosis, thickening of the epithelium (acanthosis) without any evidence of epithelial dysplasia (a pre-cancerous condition), a male predilection, and occurred mainly in patients in 50-70 years of age.

Category: Pathology MCQs