MCQ MAHE 2000 Surgery Answer 11

• Crohn's disease is a systemic disorder whose principal clinicopathological manifestation is chronic inflammation of the intestine.
  
• Any part of the gastrointestinal tract from mouth to anus may be involved in the chronic granulomatous process, but the terminal ileum and colon are the regions most frequently affected.
• Surgery is required if the disease gets out of control, or if specific complications develop. These take the form of obstruction due to stricturing, abdominal abscesses, perforation of the gut, or fistulous connections leading to discharge of intestinal content from other organs such as the bladder or vagina.
  
• About 40% of people with colonic Crohn's disease will end up with an abdominal bag collecting intestinal effluent from an ileostomy or colostomy.
• There is a very strong probability that most of Crohn's disease is being caused by Mycobacterium avium subspecies paratuberculosis (MAP)

Category: MAHE 2000 MCQs