MCQ MAHE 2000 Surgery Answer 02

The Correct Answer is A

Recognized causal influences for developing cholangiocarcinoma are:
(1) chronic liver fluke infections of the biliary tract,
(2) exposure to Thorotrast,
(3) primary sclerosing cholangitis, and
(4) congenital fibropolycystic diseases of the biliary system.

However, most cases of cholangiocarcinoma arise in the absence of any antecedent recognized risk.

EXTRA INTESTINAL MANIFESTATIONS OF IBD

- Multi system inflammatory disease
a. LIVER DISEASE - Sclerosing cholangitis , hepatitis , cholangiocarcinoma , portal hypertension etc.
b. ARTHRITIS - Mono articular involving large joints: sacroiliac / dorso lumbar involvement is most common.
- Kyphosis and ankylosis is common
c. SKIN LESIONS - Erythema nodosum , pyoderma gangrenosum , aphthous ulcers common at angles of mouth).
d. RENAL LESIONS - Nephrolithiasis / pyelonephritis (usually due to dehydration ) .
e. THYROID - Goitre, hyperthyroidism
f. VASCULITIS / THROMBOEMBOLISM
g. PERICARDITIS / PULMONARY DISORDERS
h. AMYLOIDOSIS
i. MALIGNANCY - Increased incidence of Hodgkin’s & Non-Hodgkin’s Lymphoma, squamous cell carcinoma of skin especially in Crohn's disease etc.

Category: MAHE 2000 MCQs