MCQ MAHE 2000 Medicine Answer 22
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Treatment of Pneumocystis Carinii:
- Key is early diagnosis. Mechanical ventilation along with Trimethoprin-sulfamethoxazole may reduce mortality from 80% -90% to 50%.
- TMP-SMX inhibits folic acid synthesis is relatively inexpensiveavailable in oral and parenteral forms is well tolerated and the drug of choice. Usual IV doses 15-20 mg/kg/day.
- Alternative agents Dapsone 100mg/day PO alone or in combonation with TMP-SMX.
- In patients with AIDS and CD4+ count below 200/mm3, oral candidiasis, unexplained fever of >100 F for more than 2 weeks, or recovered from previous episode of P. carinii pneunitis chemoprophylaxis is recommended and continued for life.
Tags: MCQ, Medicine, Pneumocystis Carinii
Category: MAHE 2000 MCQs
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