General Pharmacology MCQ Answer 010
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The Scatchard Plot
- It is a plot of [B]/[F] on the y-axis vs. [B] on the x-axis
- The plot is linear when a single binding site is involved; the slope being –1/Kd, and the x-intercept being BM
- You therefore now have the Kd for your drug-receptor interaction and the B max which gives you an indication of the maximum concentration of binding sites (receptors) available in the organ you drew it from.
- From all of this, you should know what goes on each axis, you should know the formula for the slope and you should know what the x-intercept is.
Category: Pharmacology MCQs
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