Warthin tumor
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The Correct Answer is B. Warthin tumor (adenolymphoma)Warthin's tumor = adenolymphoma
- occurs only in parotid gland, more common in old people, age peak: 6.-8. decade may be multicentric and bilateral
Histologically:
- the tumor has very characteristic appearance resulting from two main components-epithelial oncocytic arranged in cystic papillary structures and lymphoid stroma
- the epithelium forms cysts with papillary processes extending into them, cystic spaces are lined by bilayered epithelium with oncocytic change -abundant eosinophilic granular cytoplasm (filled with abnormal mitochondria)
- the stroma contains a variable amount of lymphoid tissue with well-differentiated germinal centres of follicles
Clinically: the tumor is benign, without recurrences-new data show polyclonal nature, malignant transformation is exceptional-carcinoma or lymphoma can develop
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