The Correct Option is
b) syphilis
Tertiary syphilis is the most commonly encountered stage with its gumma invading the mucous membrane, cartilage and bone of the nose. This stage may lead to perforation of the bony nasal septum and palate, collapse of the nasal bridge (saddle nose), scarring of the nasal passages, atrophic rhinitis and intracranial complications due to involvement of the roof of the nose. Serological tests for syphilis and biopsy are essential for diagnosis. Management is mainly through general antisyphilitic treatment (penicillin).
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