Polyarteritis nodosa

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Systemic Connective Tissue Disorders: Kawasaki Disease, Wegener's Granulomatosis, Goodpasture's Syndrome, Polyarteritis NodosaAnswer D. Polyarteritis nodosa

Polyarteritis nodosa (PAN) is a necrotizing systemic vasculitis involving the wall of small and medium sized arteries. The histologic aspect is defined by the presence of fibrinoid necrosis and an infiltrate rich in neutrophil polynuclears in the artery wall and rare granulomas. Clinical manifestations are misleading, and more often the symptoms of the disease are retrospectively related to the PAN.

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