High-risk peptic ulcers

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medEssentials for the USMLE Step 1 (Kaplan Medessenitals for the USMLE Step 1)Answer C

Re-bleeding from high-risk peptic ulcers (active bleeders and non-bleeding visible vessels) can be significantly reduced by combination therapy consisting of dual modality endoscopic intervention (epinephrine injection plus cautery) in addition to high dose intravenous PPI therapy (an 80 mg bolus followed by 8 mg/hr for up to 72 hours). High dose intravenous PPI therapy and endoscopic therapy alone are both less effective than combination therapy.

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