Physiology MCQ Answer 03
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The Correct Answer is D
Channel blockade is an important mechanism of action for toxins and some therapeutic agents. The deadly toxin 
of the puffer fish, tetrodotoxin, acts by blocking the Na+ channels that are responsible for the conduction of nerve impulse. The diuretic, amiloride, acts by blocking the Na+ channels that inhabit the apical membrane of the epithelial cells of the distal nephron. Local anesthetics such xylocaine also act by blocking ion channels. Category: Physiology MCQs
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