65 Pathology MCQs Answers
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Isotretinoin exposure is characterized by central nervous system defects (eg, hydrocephalus, microcephaly, structural errors of neuronal migration), but not meningomyelocele. Other associated abnormalities include facial asymmetry, microtia or anotia, conotruncal cardiac abnormalities, and mental deficiency. The risk for retinoic acid embryopathy is 35% in women who continue to ingest the agent past the 15th day following conception.
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